1. qPCR time course of influenza infection, measured with Influenza haemagglutinin (HA)-specific primers
2. heatmap showing qPCR analysis of antiviral and inflammatory gene expression in organoids at 2 h, 8 h, 24 h and 48 h following influenza infection

Together with reduced influenza haemagglutinin (HA) RNA levels in:

3. infected cells and viral shedding, the decrease in
4. IL6, CXCL8, IFNb1 and IFNl gene expression supports an antiviral effect of Oseltamivir in infected organoids when administered 2 h post-infection and analysed at 24 h